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Cui S, Men L, Li Y, Zhong Y, Yu S, Li F, et al

You can also search for UK-based studies via the NIHR 'Be Part of Research' portal (bepartofresearch.nihr.ac.uk), as well as ClinicalTrials.gov and the ISRCTN registry

It is engineered with two structural modifications relative to the 70-residue native protein: a substitution of arginine for glutamic acid at the third position and a 13-amino-acid extension at the N-terminus, giving a total length of 83 amino acids

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These effects are more apparent in individuals over 35 and can lead to increased demand for aesthetic treatments like dermal fillers, radiofrequency skin tightening, and collagen-stimulating injectables