In its function as a cellular caretaker, attenuation of GSTP1 expression or activity by either genetic (e.g., deletion or mutation) or epigenetic alterations may reduce cellular detoxification capacity ( Figure 2 )
however, there are important caveats: - Injection-site reactions: As with any injectable peptide, mild redness, swelling, or irritation at the injection site appear to be the most commonly reported side effects
& Vasakova, M
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Step 1: concentration Concentration is total peptide mass divided by diluent volume: 5 mg vial 3 mL = 1.667 mg/mL = 1,667 mcg/mL 10 mg vial 3 mL = 3.333 mg/mL = 3,333 mcg/mL Step 2: volume for a target amount Volume equals target dose divided by concentration