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MRS studies of glutamate and glutamine concentrations in schizophrenia have been inconsistent, with some studies reporting an increase, others reporting a decrease or no abnormality ([29,30,31,32,33,34,35], for reviews see [36, 37])

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This is a standard limitation of blend research and is why the peer-reviewed literature on individual components, rather than blend-specific data, is the primary reference for KLOW safety profiling