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The SURMOUNT trials reported that approximately 4 to 7% of participants discontinued due to adverse events, depending on dose level

Disclaimer: This spotlight is provided for educational purposes to acknowledge scientific contributions to AOD-9604 research

February 2025: Novo Nordisk announced that semaglutide 2.4 mg would be available in Mexican pharmacies by April 2025, with an average 17.5% weight loss observed in pivotal trials

Heartburn and reflux symptoms appear to occur in a subset of patients, though exact prevalence rates vary depending on the trial population and reporting methods

stage 2, metabolic risk factors (those with hypertension, hypertriglyceridemia, metabolic syndrome, or type 2 diabetes mellitus) or early CKD