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Elevated plasma concentrations of IS and pCS may arise through two distinct mechanisms: impaired clearance secondary to compromised glomerular filtration, or pathological triggering events during early disease phases (155)

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METALLURGY C07ORGANIC CHEMISTRY C07CACYCLIC OR CARBOCYCLIC COMPOUNDS C07C65/00Compounds having carboxyl groups bound to carbon atoms of sixmembered aromatic rings and containing any of the groups OH, Ometal, CHO, keto, ether, groups, groups, or groups C07C65/01Compounds having carboxyl groups bound to carbon atoms of sixmembered aromatic rings and containing any of the groups OH, Ometal, CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups C07C65/105Compounds having carboxyl groups bound to carbon atoms of sixmembered aromatic rings and containing any of the groups OH, Ometal, CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups polycyclic C07C65/11Compounds having carboxyl groups bound to carbon atoms of sixmembered aromatic rings and containing any of the groups OH, Ometal, CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups polycyclic with carboxyl groups on a condensed ring system containing two rings Landscapes Chemical & Material Sciences (AREA) Organic Chemistry (AREA) Health & Medical Sciences (AREA) Medicinal Chemistry (AREA) General Health & Medical Sciences (AREA) Hematology (AREA) Obesity (AREA) Bioinformatics & Cheminformatics (AREA) Chemical Kinetics & Catalysis (AREA) General Chemical & Material Sciences (AREA) Engineering & Computer Science (AREA) Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA) Veterinary Medicine (AREA) Pharmacology & Pharmacy (AREA) Life Sciences & Earth Sciences (AREA) Animal Behavior & Ethology (AREA) Diabetes (AREA) Public Health (AREA) Nutrition Science (AREA) Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA) Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA) Coloring Foods And Improving Nutritive Qualities (AREA) Abstract Description Die hier beschriebene Erfindung betrifft nicht-hygroskopische Salze von L-Carnitin und niedrigen Alkanoyl-L-carnitinen, die selbst vorteilhaft zur Herstellung von festen Zusammensetzungen fhren, die fr die orale Verabreichung geeignet sind

Pillich RT, Scarsella G, Risuleo G

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Landmark studies, including those published on NCBI/PubMed, have utilized microarray analysis to map GHK-Cus effect on the human genome