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Many patients see accelerated weekly weight loss as their dose increases, because higher doses strengthen appetite suppression and metabolic effects
Sutanto CN, Loh WW, Kim JE
Similarly, if injection site reactions become progressively worse rather than improving, show signs of infection (increasing warmth, spreading redness, pus, or red streaking), or fail to resolve within several days, medical assessment is warranted
Proposed mechanism is still the honest framing for that observation, because the in vivo contribution of glucagon-receptor agonism in humans is what the Phase 3 program is currently characterizing
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AGEs can damage the delicate cells in the glomerulus, leading to kidney dysfunction (Thomas 2005
