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With continued methodological innovation and mechanistic dissection, they offer a novel class of geroprotective agents that could complement existing approaches to delay senescence and treat agerelated disease

Tirzepatide activates two receptors: GLP-1 and GIP (glucose-dependent insulinotropic polypeptide)

The incoming Trump administration will have to decide whether to approve those changes

While not specifically approved for weight loss, many patients with type 2 diabetes experience notable weight reduction, sometimes exceeding 1012% of body weight, particularly at higher doses

2020;217(9): e20200785

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