Research demonstrates that postmenopausal women experience a 9% decrease in total 24-hour energy expenditure and a 30% reduction in spontaneous physical activity energy expenditure.[1] The metabolic consequences are profound: estrogen deficiency worsens insulin resistance, which is further exacerbated by the age-related increase in cortisol that promotes gluconeogenesis
DOI: 10.1186/s40360-017-0172-3 [Google Scholar] Li W, Cui M, Wei Y, Kong X, Tang L, Xu D
Current opinion in pharmacology, 7(4), 355359
Stress-induced cortisol response and fat distribution in women
Gastroenterology 151 (5), 945960.e6
Is Wegovy FDA-approved for excess body weight