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Most patients do not see the full weight loss benefit of a given dose until they have been on it for 8 to 12 weeks
The twice-daily structure requires strict adherence to 12-hour intervals
Your GP can advise on local pathways and eligibility
In a 12-month randomised clinical trial, spermidine supplementation was found to be safe, with no significant adverse effects reported
However, as observed in the SURPASS-5, daily insulin dose remained similar in participants randomized to TZP 5 and 10 mg and was mildly reduced in those assuming TZP 15 mg
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