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government adds to drug packaging
& Hsiao, E
For critical study cohorts, discard room-temperature-exposed samples and replace them
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The plasma half-life of GLP-1 is short, so GLP-1 receptor agonists (RAs) have modifications in the peptide to prolong half-life.6 As these incretin hormones are degraded by dipeptidyl peptidase-4 (DPP-4), DPP-4 inhibitors can amplify their pharmacological actions.8 Both of these two incretin-based therapies improve postprandial glucose control.6,8 Among the three drug classes, the preferred second-line treatment remains unclear ( Table 1 )
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