It is the same receptor that the hunger hormone ghrelin uses
Studies have shown that it inhibits the mRNA and protein expression of CYP1A2, CYP2D6 and CYP3A4 (Ooi et al., 2011)
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The Quercetin Paradox This duality in quercetinand its potential to be metabolized down one of two very different pathwaysis known as the "quercetin paradox." Because quercetin can oxidize so easily, forming pro-oxidant, toxic metabolites, special care must be given to how quercetin-containing products are formulated
Davis, J
Peak TC, Yafi FA, Sangkum P, et al