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A subset of genes was differentially expressed in all treatments/timepoints when UQCR-C1 was silenced, and multiple genes were differentially regulated only at specific timepoints or upon infection (all significantly differentially expressed genes are listed in Additional File 6)

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Patients should check fingerstick glucose levels and contact their healthcare provider if readings consistently exceed target ranges

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Vitamin and mineral supplementation should be individualized based on dietary intake assessment and laboratory findings rather than routinely prescribed