Keremi, B., Lohinai, Z., Komora, P., Duhaj, S., Borsi, K., Jobbagy-Ovari, G., Kallo, K., Szekely, A
Binding immunoglobulin protein (BiP/Grp78), an endoplasmic reticulum chaperon, was selected as a negative control
Oral administration is most relevant for GI-focused applications
Side Effects & Safety Injection site reactions -- redness, swelling, stinging (common with large-volume SC injections) Flu-like symptoms -- mild fever, fatigue, malaise 24-72 hours post-injection (possibly from immune clearance of apoptotic cells) GI discomfort -- nausea, mild digestive upset Temporary fatigue -- 1-3 days post-injection Off-target cell death (theoretical) -- no compound is perfectly selective
As of now, the only treatments that are available to help with the symptoms of Covid-19 long haulers are physical therapy, to restore fatigue and help patients get back to work and being on their feet
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