tirzepatide pregnancy data Does Cause Birth Defects? Evidence and Safety Guidance tirzepatide use during pregnancy GLP-1

The rapidness of weight loss on GLP-1 therapy can have visible costs

Because the medication is typically escalated gradually, most protocols begin with a low introductory dose before moving upward in 2.5 mg steps over time

Capehorn MS, Catarig A-M, Furberg JK et al (2020) Efficacy and safety of once-weekly semaglutide 1.0mg vs once-daily liraglutide 1.2mg as add-on to 1-3 oral antidiabetic drugs in subjects with type 2 diabetes (SUSTAIN 10)

Insulin resistance (IR) occurs early in the course of PCOS and is frequently present even in the absence of obesity, accounting for 60-80% of women with PCOS (26)

**Work intensity:** Big presentations, client-facing days, or long travel days are poor candidates for the nausea window

Combining GLP-1 analogues with other weight loss medications or therapies offers a personalized approach to weight management, supporting individuals on their journey to improved health and well-being