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While capsules can be administered by mouth to pigs, it was decided to introduce the capsule directly into the jejunum, since the gastric transit in the pig can be variable and of long duration, the pig stomach is more fermenting than that of a human, and the pH of the stomach is high, to the extent that enteric coating of the capsule may not give adequate protection

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Most of the participants were female (77.6%) and white (93.1%), with an average age of 47.3 years, an average weight of 106.0 kg, and an average body mass indexBMIof 38.5 kg/m

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The drug generated approximately $14 billion in revenue in 2024 and growing

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