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"Appetite suppression and reduced food cravings [are] often noticeable within the first few weeks, followed by steady weight loss over several months." Dr

Common Side Effects During Dose Increases Nausea is the most frequently reported side effect during semaglutide initiation and dose escalation, affecting up to 40% of patients in clinical trials, though severity typically decreases after 2 to 4 weeks at each dose level

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Unlike semaglutide and tirzepatide, which can be compounded because they have FDA-approved reference products, retatrutide has no approved form to compound from