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Beyond pigmentation, it influences the melanocortin system in the brain, modulating appetite, libido, and energy balance
WHO, 2023
M., Sacco, S.J., et al
Persistent or Debilitating Fatigue If your tiredness isn't improving after the first few weeks on a new dose, or if it's so severe that it prevents you from performing your daily activities such as working, caring for family, or managing your household, it's time to seek medical advice
Overweight with comorbidities In patients who are overweight and have at least one comorbidity (diabetes, high blood pressure, sleep apnea, etc.)
the hormone it imitated was discovered afterward, precisely because researchers went looking for the endogenous molecule that must exist to justify the orphan receptor
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