Originally presented at the American Diabetes Association (ADA) 82nd Scientific Sessions in 2022, the phase 3 SURMOUNT-1 trial was designed as a double-blind, randomized, controlled trial to assess the effects of 5 mg, 10 mg, or 15 mg of tirzepatide once weekly relative to placebo for weight loss
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Results from the Phase III FLOW trial showed a 20% decrease in overall mortality among type 2 diabetes patients with chronic kidney disease
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Although the changes were not significant, most of the fatty acids measured generally decreased in the L-carnitine group