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To determine, firstly, whether mean metabolite component scores in patients with stable schizophrenia differ from mean scores in healthy controls, and secondly, whether this difference is significantly leveraged by the sub-group of patients with residual schizophrenia, we regressed each component score in turn on two participant variables using a hierarchical regression model
When Yuyang Liu, a graduate student in his lab and first author of the study, compared SLC25A39s structure against others in the SLC family of transporters in the AlphaFold protein structure database, Liu spotted a unique extra loop in the protein
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