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Indeed, in both studies, the highest frequency of TEAEs was in the normal function groups, possibly owing to the smaller sample sizes in the more severe impairment groups, or alternatively because participants with more serious health concerns, such as those with severe renal or hepatic impairment, may be less likely to notice or report mild or moderate TEAEs, as observed in populations with cancer [21]

Studies in dogs with glucocorticoid induced vacuolar hepatopathy, cats with spontaneous liver disorders, and healthy cats, has proven both hepatic and RBC protective effects

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If heart rate elevation is confirmed and persistent, assess whether it is accompanied by symptoms such as palpitations, chest discomfort, or exercise intolerance

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