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Distribute across meals for optimal utilization

Rodriguez et al., 2025), with those without T2DM exhibiting even higher rates of discontinuation than those with T2DM (Rodriguez et al., 2025)

A significant subsequent advance was the construction of a de novo physical map (~340 Mb) using BioNano Genomics, which enabled a hybrid assembly that nearly doubled the N50 to 697 kb and greatly improved genome continuity (Clouse et al., 2016)

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Measurements of energy expenditure and locomotor activity HFD-induced obese C57BL/6J male mice were placed in individual small acryl calorimeter chambers with free access to HFD and water, and respiratory gas (O 2 and CO 2 ) were measured every 5 min for each individual mouse by indirect calorimetry system connected to mass spectrometer (Arco2000, ArcoSystem, Chiba, Japan)

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