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However, the extract produced a significant 15% reduction in TMAO response in female participants of premenopausal age and male participants ( n = 13), indicating potential sex-dependent cardiovascular benefits from polyphenol interventions targeting the gut microbiome-TMAO pathway
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**Daily Value (DV) not established
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NAD(+) dependent deacetylase Sirtuin 5 rescues the innate inflammatory response of endotoxin tolerant macrophages by promoting acetylation of p65
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