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(As expected, the unsaturated fatty acid oleate did not cause ER stress.) Palmitate is thought to elicit ER not by disrupting protein folding per se but by altering ER membrane fluidity, activating the UPR stress sensors through their transmembrane domains (Volmer, van der Ploeg, & Ron, 2013)
Smoking, using mouthwash with alcohol, or consuming hot beverages shortly before dosing can all affect the oral mucosa
The data were randomly rarefied to 10,000 sequences per sample before any downstream analysis
Semaglutide (Wegovy, Ozempic, Rybelsus): risk of non-arteritic anterior ischaemic optic neuropathy (NAION)
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