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Source: The New England Journal of Medicine Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff et al., 2022) Figure 1A Average Weight Loss After 72 Weeks At 72 weeks, participants taking tirzepatide once weekly lost significantly more weight than those on placebo: 5 mg dose: 15.0% average body weight reduction 10 mg dose: 19.5% reduction 15 mg dose: 20.9% reduction Placebo: 3.1% reduction All tirzepatide doses showed much greater weight loss compared to placebo
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The label states that patients with diabetes taking Wegovy in combination with those agents may have an increased risk of hypoglycemia, including severe hypoglycemia
MASLD (liver disease) trial (Nature Medicine 2024): Significant liver fat reductions (up to ~81% in some arms) alongside weight loss
For a 4 mg dose, you would draw 0.8 mL
