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Ozempic should be refrigerated before first use

Its anti-inflammatory effects include downregulation of pro-inflammatory cytokines (IL-1, TNF-alpha) and modulation of the NF-B pathway

After months of consistent weight loss on tirzepatide, the body adapts

The table treats chronic pancreatitis with fibrosis or enzyme elevation as the highest-risk row, calling GLP-1 therapy typically contraindicated there unless the patient is very carefully selected

doi: 10.21608/ejrs.2017.41822 159

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