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(Frontiers in Pharmacology, 2022) reports a half-life under 30 minutes after IM or IV administration in rodent and dog models, which is why split-dose schedules appear in the literature
2023 Aug 26;402(10403):720-730
Doi:10.1155/2015/648108 Pickart L, Vasquez-Soltero JM, Margolina A
The FDA has issued repeated warnings about companies marketing unapproved peptides as research chemicals or selling them directly to consumers online (FDA warning on unapproved drugs)
No anti-AOD9604 antibodies were detected in the subset of patients selected for antibody assay
Since B12 is water-soluble, meaning your body easily pushes out any extra through urine once youve absorbed what you need, there is no concern of overdosing on B12
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