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This represents a fundamental translational gap that must be acknowledged when interpreting the mechanistic evidence presented in this review

doi: 10.1016/j.neurobiolaging.2004.05.010 79 DorseyERShererTOkunMSBloemBR

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however, these findings are not yet sufficient to establish specificity: first, alveolar macrophages often contain inclusions of rare earth metal particles, appearing as highly electron-dense granules or grayish-white crystals