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The form for the fourth term was chosen because the data in [27] indicate that at normal cysteine concentrations (approximately 200 M) most of the flux away from cysteine is toward GSH and only a moderate amount towards other pathways
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The takeaway: strong human data on the anchor, solid pharmacology on the amplifier, and a genuine gap where the blend itself would need its own trial
Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumourigenesis
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