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But swallowing the dissolved medication sends it to the stomach, where the peptide faces degradation

Because tirzepatide affects blood sugar, it is important for patients taking other diabetes medications to be closely monitored to avoid hypoglycemia (low blood sugar).

Trials show these agents can reduce glycated hemoglobin (HbAc) by ~1% or more and induce weight reductions of 510% of body weight in many patients ( [7] ) ( [6] )

GCGR/GIPR/GLP-1R agonist: Beta: 0.65, 95%CI: 0.500.81, P = 4.44 10 16 ) and a lower level of TG (GIPR/GLP-1R agonist: Beta: -0.27, 95%CI: -0.47 to -0.07, P = 7.92 10 3

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Christoffersen B, Sanchez-Delgado G, John LM, Ryan DH, Raun K, Ravussin E (2022) Beyond appetite regulation: targeting energy expenditure, fat oxidation, and lean mass preservation for sustainable weight loss