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Table 1 Possible association between glucagon-like peptide 1 (GLP-1) and depression based on previous studies

In the landmark STEP 1 trial, published in the New England Journal of Medicine in 2021, patients taking semaglutide 2.4 mg (Wegovy) lost an average of 14.9% of their body weight over 68 weeks, compared to 2.4% in the placebo group

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