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Neurochem Res 28:13211328 Markowska AL, Ingram DK, Barnes CA, Spangler EL, Lemken VJ, Kametani H, Yee W, Olton DS (1990) Acetyl-1-carnitine

Cysteinylglycine or -glutamylcysteine have been proposed as possible alternatives.In a trial of adolescents with poorly controlled type 1 diabetes, a dose of 30-45mg/kg/day NAC failed to correct several markers of glutathione status, suggesting either a higher dose or alternative therapies may be indicated in this population.A recent study of patients with poorly controlled type 2 diabetes found that dietary supplementation of the amino acids cysteine and glycine, markers of glutathione synthesis and plasma oxidative stress were both improved

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Participants The study included 106 individuals aged 1875 years with newly diagnosed type 2 diabetes (T2D), defined as fasting blood glucose (FBG) 125 mg/dL or hemoglobin A1c (HbA1c) 6.5% at first clinical presentation