Ozempic (semaglutide) and Mounjaro (tirzepatide) are both approved for blood sugar control in patients with type 2 diabetes, but they can lead to significant weight loss too (but they are not approved for that use)
However, generally excreted does not mean entirely without consequence. Emerging research has raised questions about whether chronically elevated serum B12 levels may serve as a marker for underlying conditions or could be associated with certain health concerns
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Individuals on retatrutide, particularly for weight management, need to be aware of potential side effects, how to identify them, and when to reach out to their healthcare teams
GLP-1 and GIP Effects on the Brain Incretin receptors exist in the central nervous system
For that reason, any decision to pause or stop GLP-1 therapy should always be made in consultation with a qualified healthcare provider who can document the plan, adjust dosing, and help protect continued coverage