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Some of this was expected, since insulin is a vasodilator, but the ligand also spread more widely into hypothalamic tissue, suggesting insulin was actively promoting transport into the brain

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Zepbound (tirzepatide) is used for long-term weight management in adults with obesity (with a body mass index of 30 or higher) and overweight (with a body mass index of 27 or higher) with at least one weight-related condition, such as high blood pressure, type 2 diabetes, or high cholesterol