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We further demonstrate that GLP-1(2836) activates sAC and increases cAMP levels by increasing intracellular levels of ATP in mouse and human coronary artery smooth muscle cells (caSMCs) and human coronary artery endothelial cells (caECs), but not mouse or human CMs

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Characteristics of an Injection Flare: Significant fluid accumulation in the joint Substantial swelling and pain Symptoms appearing within 4 hours to several days after injection More intense than expected post-injection discomfort If you develop an injection flare, contact your healthcare provider