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Regarding intracellular roGFP2-based structure-function analysis of glutaredoxins, we now showed that the GSSG-dependent oxidation of the fused glutaredoxin moiety (and not the glutathionylation of the roGFP2 moiety) is rate-limiting unless saturating GSSG concentrations are present

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This means operational manufacturing that integrates new developments in areas like peptide synthesis and fill/finish

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PLoS One 7 (6), e36466

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Many patients prefer evening dosing because any initial nausea or digestive discomfort occurs while they are winding down or sleeping, rather than during work or social obligations

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