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Some research community protocols combine 5-Amino-1MQ with AOD-9604 (fat oxidation) or with a GLP-1 drug like semaglutide (appetite suppression), since the mechanisms do not overlap
Clinical Trial Evidence and Weight Loss Outcomes A Phase 2 RCT (NEJM 2023) reported approximately 24% mean body weight reduction at 48 weeks with the 12 mg dose
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Lots of research suggests such medications must be used indefinitely to maintain weight loss and related health benefits
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