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To easily visualize and quantify 3-PLGs, all nanoparticles were labelled with R6G fluorescent dye

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Gabr et al

Extracellular vesicles: exosomes and microvesicles, integrators of homeostasis

Allergic reactions remain rare but possible, especially in individuals with copper sensitivity, with symptoms including hives, swelling, difficulty breathing, and severe rash

When stratified by comparator groups, the pooled estimate was most favorable in monotherapy trials versus placebo (SMD 2.41, 95% CI 4.43 to 0.39), whereas the add-on designs versus the same background treatment (SMD 0.65, 95% CI 1.85 to 0.55), head-to-head comparisons versus another drug (SMD 0.19, 95% CI 0.84 to 0.45), and add-on designs versus placebo (SMD 0.65, 95% CI 1.35 to 0.06) showed more modest estimates and did not provide clear evidence of a between-group difference overall (p=0.21)