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Topical application (well-studied): Serums at 0.1-0.5%, creams at 0.2-1%, hair products at 0.1-0.3%

Gene expression analyses indicate upregulation of fatty-acid catabolic pathways and OXPHOS components, with partial normalization of HFD-induced dysregulation

MOTS-c: Restores mitochondria and tissue regeneration for enhanced endurance and post-injury recovery

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Most practitioners advise against use in anyone with active cancer