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Possible drug interactions with Jardiance include: Insulin and other oral diabetes medications Alcohol may affect blood glucose levels in patients with type 2 diabetes mellitus, leading to hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar)

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No adverse effects on cardiac, hepatic, renal, thyroid, or metabolic biomarkers

This is why some clinicians advocate for faster dose escalation in higher-weight individuals and slower escalation for those closer to goal weight