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These compounds activate the Nrf2 pathway, a cellular signaling system that upregulates expression of genes involved in antioxidant production including glutathione synthesis enzymes

Endotoxin contamination a common source of confounding in peptide research can trigger inflammatory responses in biological assays that mimic or mask the compounds actual biological activity

S., Navani, R., Navani, A., da Fonseca, L
doi: 10.1038/s41579-018-0001-8 42 WillettN

Restoration of rat colonic epithelium after in situ intestinal instillation of the absorption promoter, sodium caprate
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