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These include semaglutide (Wegovy) and liraglutide (Saxenda), along with newer combination agents like tirzepatide (Zepbound), which targets both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors

Efficacy and safety of monotherapy with the novel sodium/glucose cotransporter-2 inhibitor Tofogliflozin in Japanese patients with type 2 diabetes mellitus: a combined phase 2 and 3 randomized, placebo-controlled, double-blind, parallel-group comparative study

The Hypoglycemia Risk This is the most medically significant concern, particularly for patients taking tirzepatide for type 2 diabetes