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Twice daily exenatide treatment combined with metformin maintained glycemic control for longer periods and in a higher proportion of treated patients than glimepiride in an open-label, randomized controlled study in patients with inadequately controlled type 2 diabetes with up to 4.5 years of follow-up [47]

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Acknowledgments The authors wish to thank Mohammad Yassine, BPharm, MSc and Racha Aaraj, Pharm D, MSc, MPH from Phoenix Clinical Research for the support in the preparation of this manuscript

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